Nadia Khan

MD, FRCPC, MSc, ASH Clinical Specialist in Hypertension
Professor and Interim Head, Division of General Internal Medicine
Scientist, Centre for Health Evaluation and Outcome Sciences
Associate Member, School of Population and Public Health

Dr. Nadia Khan is a general internist trained at the University of Alberta and Calgary, and is a Professor of Medicine at the University of British Columbia. She is a health services researcher at the Centre for Health Evaluation and Outcome Sciences and the Department of Medicine.

Dr. Khan has published over 100 peer review papers and holds the Michael Smith Foundation for Health Research Career Scientist award. Her research interests include sex/gender/ethnic impact of cardiovascular disease, health services as well as hypertension, diabetes, and stroke. She has methodological expertise in big data, randomized clinical trials, and patient-oriented research.

Dr. Khan is co-director of the Hypertension Clinic at St. Paul’s Hospital and is an American Society of Hypertension Clinical Specialist in Hypertension. She is the current President of Hypertension Canada, and is a council member of the International Society of Hypertension. In 2016 she received the Robert E. Beamish Award, which recognizes an original study published in the Canadian Journal of Cardiology in the past three years that has the biggest potential impact on cardiovascular health and care.

Awards

Robert E. Beamish Award, Canadian Journal of Cardiology (2016)
Honour Roll for Clinical Teaching Excellence, UBC (2016)
Career Scientist Award, MSFHR (2011)
Martin M. Hoffman Award for Excellence in Research, UBC (2010)
Department of Medicine Research Award, UBC (2010)
Shelley Naiman Award, UBC (2005-2006)
Graeme Copland Clinician Teaching Award, UBC (2005-2006)
  • Health services research
  • Hypertension
  • Ethnic and gender studies in cardiovascular disease
  • Stroke
  • Diabetes
  • Big data
  • Clinical trials

Projects

A Novel Model for South Asian Treatment in Diabetes (NaMaSTe)
http://namastestudy.wixsite.com/mainpage

A CIHR-funded randomized controlled trial evaluating a novel culturally adapted diabetes program for South Asian adults with poorly controlled type 2 diabetes.

Selected Publications

Khan NA, Rabkin S, et al. Effect Of Lowering Diastolic And Systolic Blood Pressure In Patients With And Without Cardiovascular Disease: Analysis Of The Sprint Trial. Hypertension 2018. Accepted. (FA, IF: 6.9)

Daskalopoulou SS, Rabi D, Schiffrin E, et al. Khan NA. Hypertension Guidelines in the US and Canada: Are we getting closer? Hypertension 2018. Accepted. (SA, IF: 6.9)

Khan NA, Daskalopoulou SS, Karp I, Eisenberg MJ, Pelletier R, Tsadok MA, Dasgupta K, Norris CM, Pilote L; GENESIS PRAXY Team. Sex differences in prodromal symptoms in acute coronary syndrome in patients aged 55 years or younger. Heart. 2017;103(11):863-869. (FA, IF:6.0)

Khan NA. Getting to Lower Systolic Blood Pressure: Beyond Antihypertensive Therapy. Ann Intern Med. 2016;165(9):661-662. (FA, IF:17.0)

Pelletier R, Khan NA, Cox J, Daskalopoulou SS, Eisenberg MJ, Bacon SL, Lavoie KL, Daskupta K, Rabi D, Humphries KH, Norris CM, Thanassoulis G, Behlouli H, Pilote L; GENESIS-PRAXY Investigators. Sex Versus Gender-Related Characteristics: Which Predicts Outcome After Acute Coronary Syndrome in the Young? J Am Coll Cardiol. 2016;67(2):127-135. (CA, IF:19.9)

Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. Pharmacologic Management of Type 2 Diabetes: 2016 Interim Update. Can J Diabetes. 2016 Dec;40(6):484-486. Erratum in: Can J Diabetes. 2017;41(2):247. (CA, IF:1.9)

Leung Yinko SS, Maheswaran J, Pelletier R, Bacon SL, Daskalopoulou SS, Khan NA, Eisenberg MJ, Karp I, Lavoie KL, Behlouli H, Pilote L; GENESIS-PRAXY investigators. Sex differences in health behavior change after premature acute coronary syndrome. Am Heart J. 2015;170(2):242-8. (CA, IF:4.3)

Rabi DM, Daskalopoulou SS, Leung AA, Dresser G, Padwal R, Khan N. Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older. Ann Intern Med. 2017;167(4):289-290. (SA, IF:17.0)

Shah BR, Khan NA, O’Donnell MJ, Kapral MK. Impact of Language Barriers on Stroke Care and Outcomes. Stroke. 2015. (CA, IF: 6.0)

Cheung C, Martyn A, Campbell N, Frost S, Gilbert K, Michota F, Seal D, Ghali W, Khan N. Predictors of intraoperative hypotension and bradycardia. Am J Med. 2014. (SA, IF:5.3)

Ke C, P Sohal, H Qian, H Quan, Khan NA. Diabetes In The Young: A Population Based Study Of South Asian, Chinese And White Patients. Diabet Med. 2014. (SA, IF 3.24)* (Featured in: CBC, global news, BBC, Canadian Press, Toronto Star, Ottawa Citizen newspapers, OMNI television)

Padwal RS, Rabkin S, Khan N. Assessment and management of resistant hypertension. CMAJ. 2014 Aug 18. pii: cmaj.130764. (CA, IF:6.47)

Pelletier R, Lavoie KL, Bacon SL, Thanassoulis G, Khan NA, Pilote L;
GENESIS-PRAXY Investigators. Depression and disease severity in patients with
premature acute coronary syndrome. Am J Med. 2014;127(1):87-93. (CA, IF:4.77)

Khan NA, Daskalopoulou SS, Karp I, Eisenberg MJ, Pelletier R, Tsadok MA,
Dasgupta K, Norris CM, Pilote L; GENESIS PRAXY Team. Sex differences in acute coronary syndrome symptom presentation in young patients. JAMA Intern Med. 2013;173(20):1863-71. (FA, IF:10.58, cited 3 times) (Featured in an editorial in the same issue of JAMA Internal Medicine and New York Times, Global television, Vancouver Sun, CTV news, CBC radio, Huffington Post USA, Readers Digest, Heart.org, Reuter’s Health, Forbes.com, webmd.com.)

Quan H, Chen G, Walker RL, Wielgosz A, Dai S, Tu K, Campbell NRC, Hemmelgarn BR, Hill MD, Johansen H, McAlister FA, Khan N for Hypertension Outcome and Surveillance Team. Incidence, cardiovascular complications and mortality of hypertension by sex and ethnicity. Heart. 2013;99(10):715-21. (SA, IF: 6.0, cited 7 times) (Featured as Editor’s pick for top BMJ Heart Study.)

Huang K, Khan N , Kwan A , Fang J , Yun L , Kapral MK. Socioeconomic status and care after stroke: results from the Registry of the Canadian Stroke Network. Stroke, 2013, 44(2): 477-82. (CA, IF: 6.16, cited 2 times)

Rabi D, Padwal R, Tobe S, Gilbert R, Leiter L, Khan NA. Risks and benefits of intensive blood pressure lowering in patients with diabetes: Joint review by the Canadian Hypertensive Education Program and Canadian Diabetes Association. CMAJ. 2013;185(11). (CA, IF: 6.47, cited 2 times)

Conley J , Tonelli M , Quan H , Manns BJ , Palacios-Derflingher L , Bresee LC , Khan N , Hemmelgarn BR. Association between GFR, proteinuria, and adverse outcomes among White, Chinese, and South Asian individuals in Canada. American Journal of Kidney Disease 2012;59(3):390-9. (CA, IF 5.42, cited 3 times)

Quan H , Chen G , Tu K , Bartlett G , Butt DA , Campbell NR , Hemmelgarn BR , Hill MD , Johansen H , Khan N , Lix LM , Smith M , Svenson L , Walker RL , Wielgosz A , McAlister FA , Hypertension Outcome and Surveillance Team. Outcomes among 3.5 million newly diagnosed hypertensive Canadians. Canadian Journal of Cardiology, 2013, 29(5):592-7. (CA, IF: 2.75, cited 3 times)
Featured at World Health Day (April 7, 2013)

Khan NA, Wang H, Anand S, Jin Y, Campbell NR, Pilote L, Quan H. Ethnicity and sex affect diabetes incidence and outcomes. Diabetes Care. 2011;34(1):96-101. (FA, IF: 8.57, cited 14 times) (Featured in Reuter’s Health 2011, World Health Urology & News 2011.)

Fowler RA, Noyahr LA, Thornton JD, Pinto R, Kahn JM, Adhikari NK, Dodek PM, Khan NA, Kalb T, Hill A, O’Brien JM, Evans D, Curtis JR; American Thoracic Society Disparities in Healthcare Group. An official American Thoracic Society systematic review: the association between health insurance status and access, care delivery, and outcomes for patients who are critically ill. Am J Respir Crit Care Med. 2010;181(9):1003-11. (CA, IF: 11.99, cited 18 times)

Khan NA, Grubisic M, Hemmelgarn B, Humphries K, King K, Quan H. Outcomes after Acute Myocardial Infarction in South Asian, Chinese and White Patients. 2010 Circulation,122(16):1570-7. (FA, IF: 19, cited 21 times) (Featured in an editorial in the same issue of Circulation.)

Khan NA, Yun L, Humphries K, Robertson A, Silver FL, Kapral M. Antihypertensive Drug Use, Adherence and Outcomes After Stroke: Are There Sex Differences? Stroke 2010;1(7):1445-9. (FA, IF: 6.16, cited 7 times)

Khan NA, Campbell NR, Frost SD, Gilbert K, Michota FA, Usmani A, Seal D, Ghali WA. Risk of intraoperative hypotension with loop diuretics: a randomized controlled trial. Am J Med. 2010;123(11):1059.e1-8. PMID: 21035594. (FA, IF: 4.77)

McAlister FA, Herman RJ, Khan NA, Rabkin SW, Campbell N; Canadian Hypertension Education Program. Putting ACCOMPLISH into context: management of hypertension in 2010. CMAJ. 2010;182(15):1600-1. (CA, IF: 6.47)

Khan NA, Hemmelgarn B, Herman RJ, Bell CM, Mahon JL, Leiter LA, Rabkin SW, Hill MD, Padwal R, Touyz RM, Larochelle P, Feldman RD, Schiffrin EL, Campbell NR, Moe G, Prasad R, Arnold MO, Campbell TS, Milot A, Stone JA, Jones C, Ogilvie RI, Hamet P, Fodor G, Carruthers G, Burns KD, Ruzicka M, DeChamplain J, Pylypchuk G, Petrella R, Boulanger JM, Trudeau L, Hegele RA, Woo V, McFarlane P, Vallée M, Howlett J, Bacon SL, Lindsay P, Gilbert RE, Lewanczuk RZ, Tobe S; Canadian Hypertension Education Program. The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2–therapy. Canadian Journal of Cardiology 2009; 25(5):287-98. (FA, IF: 2.75)

King KM, Khan NA, Quan H. Ethnic variation in acute myocardial infarction presentation and access to care. Am J Cardiol. 2009;103(10):1368-73. (CA, IF: 3.41, cited 11 times) (Featured on OMNI Television, CTV News Calgary.)

Quan H, Khan N, Hemmelgarn B, Tu K, Chen G, Campbell N, Hill MD, Ghali W, McAlister F for the Canadian Hypertension Education Program Outcomes Research Task Force. Validation of a Case definition to Define Hypertension Using Administrative Data. Hypertension 2009; 54;1423-1428. (CA, IF: 7.63, cited 62 times)

Khan NA, Palepu A, Norena M, Ayas N, Wong H, Chittock D, Hameed M, Dodek PM. Differences in Hospital Mortality among Critically Ill Patients of Asian, Native Indian and European Descent. Chest. 2008;134(6):1217-22. (FA, IF: 7.13)

Ma IW, Khan NA, Kang A, Zalunardo N, Palepu A. Systematic review identified suboptimal reporting and use of race/ethnicity in general medical journals. J Clin Epidemiol. 2007;60(6):572-8. (SA, IF: 5.90, cited 20 times)

Hemmelgarn BR, Chou S, Wiebe N, Culleton BF, Manns BJ, Klarenbach S, Khan NA, Gourishankar S, Yeates KE, Gill JS, Tonelli M. Differences in use of peritoneal dialysis and survival among East Asian, Indo Asian, and white ESRD patients in Canada. Am J Kidney Dis. 2006;48(6):964-71. (CA, IF: 5.76, cited 19 times)

Khan NA, McAlister FA. Beta-blockers for the treatment of hypertension: a re-examination of published data. CMAJ. 2007 (FA, IF:6.47)

Khan NA, McAlister FA, Campbell NRC, Feldman RD, Mahon J, Lewanczuk R, Rabkin SW, Zarnke KB, Hemmelgarn B, Lebel M, Levine M, Herbert C, for the Canadian Hypertension Education Program. The 2006 Canadian Recommendations for the Management of Hypertension: Therapy. Canadian Journal of Cardiology. 2006;22(7):583-93. (FA, IF: 2.75, cited 70 times)

Khan NA, Hemmelgarn B, Tonelli M, Thompson C, Levin A. Troponins and Meta analysis. Circulation 2006;113(20) (FA, IF: 19)

Khan NA, McAlister FA. Beta-blockers for the treatment of hypertension: a re-examination of published data. CMAJ. 2006;174(12):1737-42. (FA, IF: 6.47, cited 101 times) (Featured in ACP Journal Club.)

Campbell NR, Khan NA, Grover S. Barriers and remaining questions on assessment of absolute cardiovascular risk as a starting point for interventions to reduce cardiovascular risk. J Hypertens. 2006;24(9):1683-5. (CA, IF: 4.22)

Khan N, Ma I, Thompson CR, Humphries K, Salem D, Sarnak M, Levin A. Kidney function and mortality among patients with left ventricular systolic dysfunction. J Am Soc Nephrol. 2006;17(1):244-53. (FA, IF: 9.50, cited 56 times)

Khan N, Rahim S, Anand S, Panju A. Does the clinical exam predict significant peripheral arterial disease? JAMA. 2006;295(5):536-46. (FA, IF: 30.39, Cited 98 times)

Khan N, McAlister F. Beta blockers for the treatment of primary hypertension. Lancet. 2006;367(9506):208. (FA, IF: 39.21)

Chou SH, Hemmelgarn BR, Wiebe N, Culleton BF, Manns BJ, Klarenbach S, Gill JS, Khan NA, Tonelli M for the Alberta Kidney Disease Network. Differences in use of peritoneal dialysis and survival among East Asian, Indo Asian and White end-stage renal disease patients in Canada. Am J Kidney Dis. 2006;48(6):964-71. (CA, IF: 5.76)

Khan NA, Hamet P, Lewanczuk RZ; Canadian Hypertension Education Program. Applying the 2005 Canadian Hypertension Education Program recommendations: 4. Managing uncomplicated hypertension. CMAJ. 2005;173(8):865-7. (FA, IF: 6.47)

Khan NA, Hemmelgarn B, Tonelli M, Thompson C, Levin A. Prognostic value of Troponin T and I among asymptomatic patients with end-stage renal disease: a meta-analysis. Circulation 2005; 112 (20): 3088-3096. (FA, IF: 19, cited 146 times) (Featured in an editorial in the same issue of Circulation)

McAlister FA, Khan NA, Straus SE, Papaiokim M, Fisher BW, Majumdar SR, Gajic O, Daniel M, Tomlinson G. The accuracy of the history, physical exam and routine tests in predicting post-operative pulmonary complications (The CARE-PREOP1 Study). Am J Resp Crit Care Med 2003;167(5):741-4. (CA, IF: 11.99, cited 33 times)

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